Reference

Loctite Selector Guide — Thread-Lockers, Retaining Compounds & Sealants

Loctite ships dozens of anaerobic adhesives, and picking the wrong one is the fastest way to strip a bolt or seize a bearing on a shaft. This guide is the shortlist we hand to MRO teams: the numbers that actually cover 90% of industrial use, sorted by job.

Thread-lockers (purple / blue / red / green)

LoctiteColorStrengthBest forSize rangeTemp
222PurpleLowSmall screws under 1/4", low-vibration adjustment screws, calibration hardwareUp to 1/4" (M6)-65 to 300°F
242BlueMediumGeneral-purpose thread-locking, allows removal with hand tools1/4" – 3/4" (M6 – M20)-65 to 300°F
243BlueMediumOil-tolerant version of 242 — works on lightly oiled fasteners without cleaning1/4" – 3/4" (M6 – M20)-65 to 360°F
262RedHighPermanent locking on studs and larger bolts; heavy vibration3/8" – 3/4" (M10 – M20)-65 to 360°F
271RedHighPermanent locking of studs, plugs and bolts up to 1"Up to 1" (M25)-65 to 300°F
272RedHigh + heatHigh-temperature red — same as 271 up to 450°FUp to 1" (M25)-65 to 450°F
277RedHighPermanent locking for very large fasteners over 3/4"3/4" – 1-1/2" (M20 – M40)-65 to 300°F
290GreenWickingWicks into pre-assembled fasteners; sealing and locking of set screws, headless boltsAny pre-assembled-65 to 300°F

Retaining compounds — bearings, bushings, keys

LoctiteColorStrengthBest forSize rangeTemp
603GreenHighOil-tolerant retaining compound for slip/press-fit cylindrical assembliesGap up to 0.005"-65 to 300°F
609GreenGeneralGeneral-purpose retaining, keys/keyways, bushingsGap up to 0.005"-65 to 300°F
620GreenHigh-tempHeat-resistant retaining compound for bearings on shafts in hot serviceGap up to 0.015"-65 to 450°F
638GreenMaxMaximum-strength retainer for slip-fit or worn parts; large gapsGap up to 0.010"-65 to 300°F
660SilverRepairRepair of worn shafts, keyways, splines; fills large gapsGap up to 0.020"-65 to 300°F
680GreenHigh + gapSlip/press-fit cylindrical assemblies with larger diametric clearancesGap up to 0.015"-65 to 300°F

Thread sealants — pipe fittings, hydraulic, pneumatic

LoctiteColorStrengthBest forSize rangeTemp
545PurpleLow pressureHydraulic and pneumatic thread sealant for fine threadsUp to 3/4"-65 to 300°F
565WhiteGeneralControlled-strength thread sealant for stainless & coated fittingsUp to 2"-65 to 300°F
567WhiteHigh-tempPTFE-filled sealant for tapered pipe threads on stainless & coated fittingsUp to 3"-65 to 400°F
592WhiteSlow cureSlow-cure thread sealant giving longer working time on large fittingsUp to 3"-65 to 400°F

Quick decision rules

242 vs 243: both are medium-strength blue. Use 243 if the fastener is oily and you can't clean it; otherwise 242. 243 also has a wider substrate tolerance and slightly higher temp rating.

271 vs 272: both are high-strength red. Pick 272 if the joint sees temperatures above 300°F (steam, exhaust, motor housings). Otherwise 271 is the default red.

Retainer selection: choose by diametric gap. Under 0.005" use 603 / 609; up to 0.010" use 638; up to 0.015" use 680; larger gaps or worn shafts use 660.

Pipe sealant: for stainless or coated fittings use 567 (PTFE-filled, high-temp). For general steel pipework 545 handles hydraulics and pneumatics up to 3/4" fittings.

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